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The Wagner Lab
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Research Projects
Blood Brain Barrier (BBB)
- Relationship between BBB function and Alzheimer's disease
- Imaging of BBB permeability by multiphoton microscopy in live mice
- Development of a stroke model
Thrombosis
- Molecular mechanisms involved in platelet aggregation
- Role of GPIb, CD40L, integrins and their ligands
- Role of metalloproteinases ADAMTS13 and TACE (ADAM17) in platelet function and thrombus formation
Coagulation
- Cell biology and signalling in pro-coagulant microparticle generation
- Role of P-selectin and PSGL-1
Atherosclerosis
- Pathways in atherosclerotic lesion formation and maturation
Angiogenesis
- Role of platelets in angiogenesis in in vivo models