Images and Key Papers
This page lists some important images, as well as our key papers. You can also view all of our publications.
Images
- The major classes of adhesion receptors, shown embedded in a putative plasma membrane
- Interactions between blood cells and stimulated or injured venule
- Endothelial cell with Weibel-Palade bodies
- Platelet rolling on stimulated mesenteric venules
- Basal intravital leukocyte rolling in mesenteric venules
- Aortic sinus lesions in LDLR-deficient mice on diet for 8 weeks
- Leaky blood brain barrier in apoE-/- mice
- Effect of recombinant soluble CD40L on human thrombi growth at shear rate 1000/s
- P-sel-Ig treatment of hemophilia A mice generates procoagulant microparticles and accelerates the onset of clotting
Key Papers
- Wagner, DD, Olmsted, JB, Marder, VJ.
Immunolocalization of von Willebrand protein in Weibel-Palade bodies of human endothelial cells.
J Cell Biol. 95:355-360, 1982. [Abstract] - Sporn, LA, Marder, VJ, Wagner, DD.
Inducible secretion of large, biologically potent von Willebrand factor multimers.
Cell. 46:185-190, 1986. [Abstract] - Bonfanti, R, Furie, BC, Furie, B, Wagner, DD.
PADGEM (GMP140) is a component of Weibel-Palade bodies of human endothelial cells.
Blood. 73:1109-1112, 1989. [Abstract] - Larsen, E, Celi, A, Gilbert, GE, Furie, BC, Erban, JK, Bonfanti, R, Wagner, DD, Furie, B.
PADGEM protein: a receptor that mediates the interaction of activated platelets with neutrophils and monocytes.
Cell. 59:305-312, 1989. [Abstract] - Wagner, DD, Saffaripour, S, Bonfanti, R, Sadler, JE, Cramer, EM, Chapman, B, Mayadas, TN.
Induction of specific storage organelles by von Willebrand factor propolypeptide.
Cell. 64:403-413, 1991. [Abstract] - Mayadas, TN, Johnson, RC, Rayburn, H, Hynes, RO, Wagner, DD.
Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice.
Cell. 74:541-554, 1993. [Abstract] - Frenette, PS, Johnson, RC, Hynes, RO, Wagner, DD.
Platelets roll on stimulated endothelium in vivo: an interaction mediated by endothelial P-selectin.
Proc Natl Acad Sci U S A. 92:7450-7454, 1995. [Abstract] - Frenette, PS, Mayadas, TN, Rayburn, H, Hynes, RO, Wagner, DD.
Susceptibility to infection and altered hematopoiesis in mice deficient in both P- and E-selectins.
Cell. 84:563-574, 1996. [Abstract] - Denis, C, Methia, N, Frenette, PS, Rayburn, H, Ullman-Cullere, M, Hynes, RO, Wagner, DD.
A mouse model of severe von Willebrand disease: defects in hemostasis and thrombosis.
Proc Natl Acad Sci U S A. 95:9524-9529, 1998. [Abstract] - Andre, P, Hartwell, D, Hrachovinova, I, Saffaripour, S, Wagner, DD.
Pro-coagulant state resulting from high levels of soluble P-selectin in blood.
Proc Natl Acad Sci U S A. 97:13835-13840, 2000. [Abstract] - Ni, H, Denis, CV, Subbarao, S, Degen, JL, Sato, TN, Hynes, RO, Wagner, DD.
Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogen.
J Clin Invest. 106:385-392, 2000. [Abstract] - André P, Prasad KSS, Denis CV, He M, Papalia JM, Hynes RO, Phillips DR and Wagner DD.
CD40L stabilizes arterial thrombi by a β3 integrin-dependent mechanism.
Nature Med. 8: 247-252, 2002. [Abstract] - Hrachovinova I , Cambien B, Hafezi-Moghadam A, Kappelmayer J, Camphausen RT, Widom A, Xia L, Kazazian HH, Schaub RG, McEver RP, Wagner DD.
Interaction of P-selectin and PSGL-1 generates microparticles that correct hemostasis in a mouse model of hemophilia A.
Nat Med. 9: 1020-1025, 2003. [Abstract]